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Health 1 SOURCE · UNCORROBORATED ≈NATIONAL Jul 16, 2026

FDA approves Merck's first-in-class oral PCSK9 drug

The FDA has approved Merck's first-in-class oral PCSK9 drug, Lipfendra, for high cholesterol on a national level. In six-month trials, the drug reduced LDL cholesterol by up to 60 percent. Its real-world impact is not yet known as the treatment is newly approved.

Why it matters

This provides the first oral option for patients who need PCSK9 inhibitors, a class of drugs previously only available as injections.

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